A Paradigm Change in the Treatment
Strategy for uHCC

Take home messages
1. Preserved liver function and choosing a SAFE therapy are important to deliver longer and effective treatment
2. The best shot should be used at the frontline in HCC treatment.
3. Atezo + Beva is the standard 1st line treatment for advanced HCC
4. The potential treatment options after 1st line Atezo + Beva combination treatment include lenvatinib and sorafenib according to JSH recommendation, but the evidence is still missing